Study of glycated haemoglobin, lipid profile and uric acid levels in diabetic retinopathy

Diabetic patients with and without complications show a difference in serum uric acid pattern in relation to duration of disease along with glycemic status, lipid derangements and complications associated with the disease. HbA1c studies were taken to know the blood sugar levels for the past 3 months to assess the glycemic control. Study of lipid profile is also taken to assess the micro vascular complications like Retinopathy in diabetic cases. Behaviour of uric acid levels may indicate the ongoing patho physiology in diabetes in relation to glycemic control, onset and progression of complications such as retinopathy. The present study consists of 75 cases of chronic diabetes with retinopathy as a complication in the age of 45-75 years. The values are compared with the values of 50 apparently healthy non-diabetics which will fall on the same age group. All the subjects were from ophthalmology department of Govt. General Hospital, Kakinada and also from Nayana Eye Care Hospital, Kakinada. The Mean, SD Values of HbA1C were high in whole blood group of diabetic retinopathy cases, 8.903, +1.549 as compared to control group. The Mean, SD values of uric acid of diabetic retinopathy cases are 4.796, +0.944, which doesn‟t show much difference with control group, It shows that poor glycemic control plays a major role on the onset and progression of diabetic retinopathy. In diabetic retinopathy statistically significant lipid profile changes observed. Serum uric acid level has not shown statistically significant changes in diabetic retinopathy. It shows that uric acid values have no significance.